Comprehensive physician-reviewed information about basal cell carcinoma, including warning sign photos, treatment options, symptoms, and risk factors. Skin nonmelanocytic tumors – Basal cell carcinoma (BCC) Nodular: Large tumor nodules in the dermis; Generally circumscribed. Superficial. Different variants as nodular, cystic, micronodular, superficial, pigment BCC are Nodular basal cell carcinoma comprises about % of the cases and.

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When Menzies criteria are used; however, the final diagnosis is made by histopathology. Dermoscopy showing telangiectatic vessels. As well as sugary is one of the initial historically method for BCC treatment. Abstract Basal cell carcinoma BCC is the most common paraneoplastic disease among human neoplasms. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.

Some superficial cancers respond to local therapy with 5-fluorouracila chemotherapy agent. The pigmentation can be found in different clinical versions of basal cell carcinoma including nodular, micronodular, multifocal and superficial BCC, and the color varies from dark brown to black [ Figure 8 ].

The high doses of UV light induct free oxygen radicals, which combined with the reduced antioxidant protection system result in different degeneration processes inclusive carcinogenesis. Georgi Sofiiski Str, Sofia, Bulgaria. For the skin condition in cats, see Eosinophilic granuloma. Nutrition for Healthy Skin: The Journal of Dermatologic Surgery and Oncology.

Images hosted on PathOut server: Generally, this method is used on cosmetically unimportant areas like the trunk torso. It is not applied in the area of the eyes, nose, lips, and cochlea.


Cystic BCC One or more cystic nodes with different sizes located peripherally to the centrally placed tumor nests. Risk of recurrence according to adequacy of surgical margins”. Nil Conflict of Interest: Basal-cell carcinomas can often come in association with other lesions of the skin, such as actinic keratosisseborrheic keratosissquamous cell carcinoma.

Basal Cell Carcinoma (BCC) –

This further softens the skin, allowing for the knife to cut more deeply with the next layer of curettage.

This clinical version is often underestimated when the borders of surgical excision are estimated. About two thirds of basal-cell carcinomas occur on sun -exposed areas of the body. One-third occur in non-sun-exposed areas; thus, the pathogenesis is more complex than UV exposure as the cause. Recurrent cancers are much harder to cure, with a higher recurrent rate with any methods of treatment.

The lesions are solitary, seldom numerous, the most common location is on the skin of the back and affect especially women. Lobular carcinoma in situ Invasive lobular carcinoma. Archived from the original on 5 July Please review our privacy policy. J Am Acad Dermatol. Pigment basal cell carcinoma The pigmentation can be found in different clinical versions of basal cell carcinoma including nodular, micronodular, multifocal and superficial BCC, and the color varies from dark brown to black [ Figure 8 ].

A meta-analysis of randomized controlled trials supports surgery as the most effective treatment of BCC of the skin. The hemorrhagic carcinomma can resemble hemangioma or melanoma, especially if are pigmented.


This article has been cited by other articles in PMC. Examination, skin biopsy [3].

The skin is then burned with an electric current. Archived from the original PDF on One can expect a great deal of inflammation with this treatment. Immunotherapy research suggests that treatment using Euphorbia peplusa common garden weed, may be effective.

J Cutan Med Surg. The regression areas are presented as pale sections with fibrosis. Small cell carcinoma Combined small cell carcinoma Verrucous carcinoma Squamous cell carcinoma Basal cell carcinoma Transitional cell carcinoma Inverted papilloma. J Skin Cancer ; Basal cell carcinoma plus admixed foci indistinguishable from squamous cell carcinoma NOT the same as focal squamous differentiation in BCC, which is commonly seen More aggressive than classic basal cell carcinoma J Am Acad Dermatol ; Seldom had the paresthesia or hyperesthesia as a symbol of perineural infiltration appeared, especially when the tumor is localized on face.

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Recurrence rates of treated basal cell carcinomas. Basal-cell cancer is a very common skin cancer.

Clinical variants, stages, and management of basal cell carcinoma

The British Journal of Dermatology. Genetics of basal cell carcinoma. It has limited use in nodular-ulcerative and superficial BCC, but there is a high degree of relapses because of underestimating of the lesion depth. The melanocytes are located among tumor nests, while the melanophages are present in the stroma.